ENGINEERING MICROBIAL COMMUNITIES

This research goes beyond sub-cellular circuitry and explores the design of multi-cellular systems

Engineered synthetic microbial communities comprise (multiple) defined species that are functionally interlinked using rationally engineered metabolic, genetic and physical interactions. The resulting systems provide catalytic activities of industrial value or in situ delivery of bioactive molecules.

Current Theme Members

Dr Munehiro Asally

Assistant Professor, School of Life Sciences

Design principles in bacterial biofilm formation for synbio applications using interdisciplinary approaches including modelling and quantitative time-lapse imaging.

M.Asally@warwick.ac.uk Website

Dr Yin Chen

Associate Professor, School of Life Sciences

Microbial diversity, genetics and biochemistry of microorganisms involved in methylated amine and quaternary amine metabolism in the human body and terrestrial and marine ecosystems.

Y.Chen.25@warwick.ac.uk Website

Dr Joseph Christie-Oleza

NERC Independent Research Fellow, School of Life Sciences

Microbial interactions occurring between photosynthetic and heterotrophic marine microbes: culture physiology; molecular pathways; secreted products.

J.Christie-Oleza@warwick.ac.uk Website

Dr Eleanor Jameson

WISB Research Career Development Fellow

Gut microbiology, quaternary amine metabolism, microbial communities, genetics.

Eleanor.Jameson@warwick.ac.uk Website

Dr Kevin Purdy

Associate Professor, School of Life Sciences

Fundamentals of microbial ecology, including microbial community structure and function. Study of microbial communities involved in global biogeochemical cycling.

K.Purdy@warwick.ac.uk Website

Dr Hendrik Schäfer

Associate Professor, School of Life Sciences

Microbial biotech, microbial communities, metagenomics, sulfur cycling, degradation of volatile sulfur compounds, biodegradation of aromatic compounds, methylotrophs.

H.Schaefer@warwick.ac.uk Website

Dr Orkun Soyer

Professor, School of Life Sciences

Co-Director | Theme Lead | SynBio CDT Associate Director

Engineering signaling and metabolic systems, including  microbial communities for anaerobic digestion.

O.Soyer@warwick.ac.uk Website

Recent Publications

Manganese oxide biomineralization is a social trait protecting against nitrite toxicity
C. Zerfaß, J. A. Christie-Olezaa, O. S. Soyer
bioRxiv
April 04, 2018
Engineering microbial communities using thermodynamic principles and electrical interfaces
C. Zerfaß, J. Chen, O. S. Soyer
Current Opinion in Biotechnology
December 18, 2017
Permeable Protein-Loaded Polymersome Cascade Nanoreactors by Polymerization-Induced Self-Assembly
L. D. Blackman, S. Varlas, M. C. Arno, A. Fayter, M. I. Gibson, R. K. O’Reilly
ACS Macro Letters
October 31, 2017
Impact of spatial organization on a novel auxotrophic interaction among soil microbes
X. Jiang, C. Zerfaß, R. Eichmann, M. Asally, P. Schaefer, O. Soyer
bioRxiv
September 28, 2017
An integrated computational-experimental approach reveals Yersinia pestis genes essential across a narrow or a broad range of environmental conditions
N. J. Senior, K. Sasidharan, R. J. Saint, A. E. Scott, M. Sarkar-Tyson, P. M. Ireland, H. L Bullifent, Z. Rong Yang, K. Moore, P. C. F. Oyston, T. P. Atkins, H. S. Atkins, O. S. Soyer, R. W. Titball
BMC Microbiology
July 21, 2017

WISB has been funded by the above bodies